Endotoxin Free Reagents for Critical Life Science Applications

Ultra-low endotoxin (<0.005 EU/mL) products designed for cell therapy, biologics manufacturing, and sensitive life science workflows.

Introducing EndoToxFree™ Reagents

• Ultra-low endotoxin levels (<0.005 EU/mL) eliminate interference that can compromise your critical experiments
• USP Grade quality ensures high purity and consistent composition from batch to batch
• Calcium and magnesium-free formulation gives precise control over cell behavior
• Reliable, reproducible results across manufacturing lots
• Regulatory compliance support for smooth transitions from research to GMP manufacturing

Buy standard catalog items now.
Use the links in the EndoToxFree™ Product Specification Table below to go straight to the product ordering page!

EndoToxFree™ Product Specifications & Technical Highlights

 

Product Name	Item #	Quantity	Key Benefit	Technical Highlights
EndoToxFree™ DPBS (1X), USP Grade	114-348-101	500 mL	Gives you precise control over cell behavior, preventing unwanted adhesion and ensuring clean enzymatic reactions	Endotoxin level <0.005 EU/mL USP Grade Calcium and Magnesium Free Quality Tested for endotoxin level, sterility, and mycoplasma
EndoToxFree™ PBS, pH 7.4, USP Grade	114-322-131	1000 mL	Use to maintain pH in a variety of biological and cell culture applications including washing cells before dissociation, transporting cells or tissue, diluting cells for counting, and preparing reagents.	Endotoxin level <0.005 EU/mL USP Grade Calcium and Magnesium Free Quality Tested for endotoxin level, sterility, and mycoplasma pH 7.3 – 7.5
Water, Endotoxin Free	118-325-101 118-325-101CS 118-325-131 118-325-131CS	500 mL Case of 10 x 500 mL 1000 mL Case of 10 x 1000 mL	Ideal for producing ultra-low, endotoxin serum-free media and buffers for transfection, transformation, cell and tissue culture. Suitable when testing under pyrogen-free conditions (LAL testing) is required. Reliable for rinsing and washing equipment, glassware, and plasticware in pyrogen-free conditions.	Endotoxin level <0.005 EU/mL Quality Tested for endotoxin level, sterility, and mycoplasma DNase, RNase, and Protease

Technical FAQ

Q: What makes EndoToxFree™ reagents different from standard laboratory-grade buffers?
A: Standard reagents often contain trace levels of endotoxins that can stimulate Toll-like receptors (TLRs), leading to unintended cellular activation or experimental variability. Our EndoToxFree™ line is manufactured using USP-grade raw materials and ultra-pure water, ensuring endotoxin levels are consistently below 0.005 EU/mL.

Q: Are these products suitable for cGMP manufacturing environments?
A: Yes. Our reagents are manufactured under an ISO 9001:2015 certified and GMP-compliant quality management system. We provide full traceability and Certificates of Analysis (CoA) for every lot, making them ideal for the transition from R&D to clinical-stage manufacturing.

Q: Can I request a custom volume or specific packaging for the new EndoToxFree™ PBS (1X), pH 7.4?
A: Absolutely. Quality Biological specializes in custom formulations and flexible packaging, including single use bioprocess bags. Please use the “Consult with a QBI Scientist on Custom Volumes of EndoToxFree™ Reagents” form to specify your requirements.

Q: How are the endotoxin levels verified?
A: Every lot is tested using the Limulus Amebocyte Lysate (LAL) kinetic chromogenic method, the industry gold standard for sensitivity and accuracy.

Why partner with Quality Biological?

For over 40 years, Quality Biological has partnered with clients to develop, optimize, and scale up their custom media formulations.

At Quality Biological, we are committed to empowering your success. We provide unique solutions tailored to your specific challenges, increase your efficiency, and save you time.

We help you achieve your goals faster by focusing on delivering the highest-quality solutions. Our manufacturing facility operates under a stringent ISO 9001:2015 certified quality management system (QMS), ensuring that each batch meets the highest consistency and reliability standards.

Need help with a project? Schedule a consultation with a QBI Scientist today to discuss your unique needs.

Whether you need resources to assist you in developing a formulation or help optimizing and scaling a current formulation, we can provide customized options to get you to your goal faster.